Our Research

---

Our genomics and translational bioinformatics research aims to identify the strong and weak points in the human genome as they relate to health and disease risk. We're diving deep into human genomes and integrating multi-omics level data to improve personalized medicine and find actionable targets for rare and age-related diseases.

Cancer treatments have advanced dramatically in recent years. But we're researching platforms aimed at detecting cancer at its earliest stages and preventing it altogether.

Aging connective tissue and decaying ECM remain underappreciated and under-researched areas of human aging research and therapeutic development. At ICR, we take several approaches to these issues, including researching connective tissue diseases like Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorder for clues to develop effective therapeutics.

Preventing age-related cognitive decline and dementia goes hand-in-hand with research to repair and restore damaged and lost brain cells at ICR.

Ischemic heart disease is the world's biggest killer. We are researching practical ways to prevent and reverse atherosclerosis as well as repair aged, damaged vasculature.

Stroke is a major cause of death and debilitation in aging adults. Research into stroke prevention and repairing the aging neurovascular system is central to our mission.

Osteoarthritis is a primary contributor to age-related frailty. We are researching novel, practical ways to regenerate cartilage and repair osteoarthritic joints.

The aging immune system underlies most age-related disease, including atherosclerosis, cancer, neurodegeneration and frailty. Regenerating the aged immune system is key to successfully combating aging.

Researching new methods to detect, quantify and track health and disease biomarkers is critical to making healthcare decisions. The more high-quality information one has, the better informed one's decisions can be. Our In Vitro Diagnostics and Biomarkers Program works with all of our other aging- and disease-related programs to ensure successful tracking of key biomarkers.