Principal Scientist - Cancer Vaccines

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ICR's Cancer Prevention science centers on developing preventive cancer vaccines. We are hiring a Principal Scientist with a deep background in peptide-based vaccine development, cancer immunology and immuno-oncology. As part of our mission to prevent age-related disease, training human immune systems to spot and destroy cancer before it becomes a problem is critical. We truly believe that an ounce of prevention is worth a pound of cure. 

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With us, you'll get to:

• Lead ICR's Cancer Prevention Group in researching and developing novel preventive cancer vaccines
• Drive end-to-end design, execution and interpretation of preclinical vaccine studies, directly shaping the path to human translation
• Collaborate closely external KOLs and CRO partners to turn cutting-edge cancer immunology insights into first-in-class preventive vaccine programs

Please apply if you have:

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• A PhD, MD or both and at least 10 years of vaccine development experience, preferably cancer vaccines
• In-depth knowledge of and experience researching personalized cancer vaccines, including peptide-based vaccines and neoantigen-based cancer vaccines
• Extensive experience with vaccine epitope identification, selection/prioritization (of neoantigens), vaccine adjuvants and immune response monitoring
• Experience with molecular T cell receptor repertoire analysis and tracking, T cell proliferation assays, cytokine release assays and ELISPOT
• Experience deriving antigen-specific T cell clones and lines
• Expertise in cancer stem cell antigens, tumor-associated antigens, neoantigens, immuno-editing and immuno-monitoring
• Extensive knowledge of and experience with vaccine delivery systems, including peptide-, cell- and viral-based systems
• The ability to work well with CROs and manage external projects
• Even if you don't meet all of these criteria, please apply anyway

And you'll need:

• The ability to work in the United States without sponsorship
• To have an easygoing, hard-working personality

Starting base pay range: $165,000/yr - $215,000/yr

Starting additional compensation range: $7,500/yr - $20,000/yr

Starting position title and compensation are commensurate with experience.